Holy crap, thanks a bunch for all the info. I'll go with the custom build.
BloodyT: It is the Antec Gamer 900 with window case.
I'm not set on the Gigabyte board but just picked one from another build I saw and liked what Pedro said about them on another thread I came across. There are many more Asus options on their list to choose but I'll have a look to see if the Gigabyte GA-EP35-DS3R (rev. 2.1) you mention, Pwnzilla. EDIT: I didn't see that available.
What Asus motherboard would you use with this build, if you were to recommend one? This building outfit seems to prefer Asus looking at the choices.
Fluffy, what issues have you had with Gigabyte boards?
I also know the 2.1 is not going to fully reap all bens of that sound card (it's the XFi Gamer version offered, they do have the Fata1ity but it's running at $115 more up here for some reason) but I HATE wires and loads of little speakers everywhere of the 5.1 set up. I like headsets a lot so I'll be okay. EDIT: I went back and looked and there is a Fatal1ty Pro and Fatal1ty Champion series...I was quoting the Champion series.....the Pro series is only $55 more).
Thanks all for the Physics Accelerator opinions...looks like a gimmick now to me.
Thanks also for clarifying that Dell system is only 32 bit OS and why that is not so good.
Pwnzilla, I'll look into the PSU choice as well and see if I can upgrade. I'll also specifically mention the "large heatpipe/sinks on the dimms. Those can create clearance issues/obstructions with some mobo layouts and/or CPU heatsinks" issue when I order and let them confirm if the clearance is there. EDIT: Just selected the PC P&Cooling 750W, 60A, 12V Rail, Quad PCIe, Crossfire Certified...
I'm not pleased to have to buy a system right now but if I'm going to do it and slap a wad on my plastic, then it had better be good and somewhat future proofed. I want to get 5 years out of it.
FLUFF, Dal could do it (so could I with instructions) but I want a warranty! I want someone to blame and cry and point at if it all goes to hell.
Thanks again guys. Very much appreciated.